The toxic shock syndrome.

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Toxic shock syndrome

Toxic shock syndrome is an acute febrile illness with mucocutaneous manifestations and multisystem involvement, often associated with focal staphylococcal infection. Although Todd originally described the disorder in children,' with a subsequent report of childhood toxic shock syndrome,2 publicity given to the disorder in relation to menstruation and tampon use has resulted in its being conside...

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Toxic shock syndrome.

The entity of the variable pictures of an illness summed up by the description "toxic shock syndrome" has been focussed on by a great number of publications in Northern America since 1978, but has been described scarcely until yet in Germany. An etiological relationship with formerly described "toxic scarlet fever" and "Kawasaki syndrome" is to be discussed. This case in charge deals with a 25-...

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The Staphylococcal Toxic Shock Syndrome

Toxic shock syndrome toxin 1 (TSST1)t is a 22-kD exotoxin produced by most strains ofStaphylococcus aureus isolated from patients with toxic shock syndrome (TSS) (1) . TSST1 is a potent activator of monocytes and T cells . It acts on monocytes to induce the synthesis of IL-1 and TNF (2-4) . TSSTl also triggers T cell activation and proliferation (5), as well as the production of large amounts o...

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Toxic Shock Syndrome (TSS)

Toxic Shock Syndrome, otherwise known as TSS, is a systemic infection that is associated with the bacteria Staphylococcus aureus [1]. S. aureus exists as part of the human body’s normal bacteria, and does not cause infection since most people develop antibodies against the bacteria. Infection can be result in people that have not developed these antibodies, or may develop in people that have an...

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Toxic-shock syndrome.

In the past 10 years, we have learned much about TSS and S. aureus and its toxins. A number of important biologic principles have been reemphasized in this first decade of TSS research: S. aureus is a very complex organism, one not likely to yield quick answers; in vitro observations must always be confirmed in the patient; animal models may not always be reliable replicates of human disease; a...

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ژورنال

عنوان ژورنال: BMJ

سال: 1990

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.300.6730.960